Research and Surveys
Double blind randomised trials are not ideally suited to testing the efficacy of homoeopathy as each prescription is individualised to match the patient. For example, 15 people with arthritis may all need a different homoeopathic remedy.
In 2014, the research team of Mathie et al. carried out a systematic review and meta-analysis of individualised homoeopathic treatment as delivered by homoeopaths in practice versus placebo.
They found that when used in this way, homoeopathic remedies are 1.5-2 times more effective than placebo. Read more about it here.
Ultra High Dilutions
Dissolved molecules would be expected to spread further and further apart, but chemists Kurt Geckler and Shashadhar Samal in South Korea made a chance discovery. Particles of diluted substances that thy observed clustered together, becoming larger aggregates of those clusters. This could tie in with homoeopathic remedies becoming more powerful despite being more dilute. Read more here.
In 2007 a systematic review of 67 experiments published in 75 publications evaluated the entire in vitro (test tube) evidence base for the effects of high potency homoeopathic medicines. 75% of these found that ultra high dilutions have effects.
Witt CM, Bluth M, Albrecht H, et al, The in vitro evidence for an effect of high homeopathic potencies - a systematic review of the literature, Complement Ther Med, 2007; 15: 128-138.
Ultra high dilutions under experimental conditions have been shown to have effects such as homoeopathic dilution of histamine altering the activity of white blood cells (Belon P. Crumps J. Ennis M, et al. Histamine dilutions modulate basophil activation, Inflammation Research, 2004; 53: 181-8)
Also homoeopathic thyroxine slowing down the metamorphosis of tadpoles into frogs (Endler PC, Heckmann C, Lauppert E, et al. The metamorphosis of amphibians and information of thyroxine. In: Schulte J, Endler PC (eds). Fundamental Research in Ultra High Dilution and Homoeopathy. Dordrecht: Kluwer Academic Publishers, 1998.)
"I can't manage without homoeopathy. In fact, I never go anywhere without homoeopathic remedies. I often make use of them." Paul McCartney